The total value of land for sale in McCook County recently on Land.com was nearly $9 million. This represents 1,000 acres of land for sale in McCook County. McCook County ranks 18th out of 66 counties in South Dakota for the combined amount of land currently advertised for sale. Among cities in McCook County with land for sale, Canistota had the most land for sale. Its economy is defined as agricultural, with 568 farms recorded in the county during the most recent U.S. Census. Farming activities in McCook County generate annual revenues of $39 million, most of which is from crops. McCook County is South Dakota's 53rd biggest county (576 square miles). It's located in the Southeast South Dakota region of South Dakota.