The value of all farms, ranches, hunting land and other land for sale in Mississippi County recently was around $20 million, representing a combined 1,501 acres of land for sale in Mississippi County. Mississippi County ranks 93rd in the Ozark State for the combined amount of land currently advertised for sale. Of all locations in Mississippi County with farms and ranches for sale, Charleston featured the most land for sale. Mississippi County is the 103rd largest county (428 square miles) in Missouri. It's located in the Southeast Missouri region of the state.