Of 115 counties in the state, Mississippi County ranks 103rd in terms of size (428 square miles). Mississippi County is in Southeast Missouri. Missouri's Mississippi County has around 1,000 acres of ranches for sale based on recent Land Network data. The combined market value of land and rural real estate for sale here was almost $1 million. Browse all Mississippi County ranches for sale on the Land Network to find the ranch that's right for your business or commercial needs, from the sprawling legacy ranch to unbelievable residential ranch for your second home, investment property or retirement nest egg. The most common type of land for sale by combined acreage in Mississippi County is house.