A combined nearly 2,000 acres were listed for sale in Monroe County recently; the value of all Monroe County land and rural real estate for sale was $25 million. Monroe County ranks 78th in the state for the total number of acres of land currently advertised for sale. Madison featured the most land for sale. Monroe County has a large agricultural economy, with 1,061 farms recorded in the county during the latest U.S. Census. Farming activities in Monroe County generate annual revenues of $24 million, most of which is from crops. Monroe County is Missouri's 40th largest county (670 square miles). It's located in the Northeast Missouri region of Missouri.