A total of approximately 4,000 acres were listed for sale in South Carolina's Pickens County recently; the value of all Pickens County farmsand rural real estate for sale was almost $485 million. Pickens County ranks 11th in the Palmetto State for the total acreage of land currently advertised for sale. There were two properties listed as sold in Pickens County through the Land Network Comparable Sales Program. This represented a total value of $13,644,999. Of all farms and rural real estate for sale in Pickens County, Easley had the most land for sale. Government and state-level services are the main economic drivers in Pickens County. Pickens County is the 33rd largest county (512 square miles) in South Carolina. It's located in the Upstate South Carolina region of the state.