There was a total of around $13 million of land for sale in Brule County recently on Land.com. The total size of all Brule County land and rural real estate for sale was 2,000 acres. Brule County ranks 27th in the Coyote State for the combined amount of land currently advertised for sale. Of all land for sale in Brule County, Chamberlain had the most land for sale. Its economy is defined as agricultural, with 407 farms recorded in the county during the most recent U.S. Census. Farming activities in Brule County generate annual revenues of $12 million, most of which is from crops. Brule County is the 38th largest county (846 square miles) in South Dakota. It's located in the Great Lakes South Dakota region of South Dakota.